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Depo-Provera and Meningioma: What You Need to Know

By: Anapol Weiss

When it comes to managing birth control, women have numerous options available to them, from oral contraceptives to long-acting methods like Depo-Provera. Depo-Provera, an injectable form of birth control, has been a popular choice due to its convenience and efficacy. However, a recent study linked Depo Provera use to an increased risk of brain and spinal tumors called meningiomas. It is estimated that 1 in 5 women have used Depo-Provera at some point which makes these findings concerning for many.

What is Depo-Provera?

Depo-Provera is a brand name for a contraceptive injection containing medroxyprogesterone acetate, a synthetic form of the hormone progesterone. The injection is generally administered every three months and works by preventing ovulation, thickening cervical mucus, and thinning the lining of the uterus to prevent pregnancy. It may also be used in the treatment of endometriosis, abnormal uterine bleeding and ovarian cysts. Depo-Provera has been widely used in the United States with an estimated 1-2 million women using it yearly.

What are Meningiomas?

Meningiomas are tumors that arise from the meninges, the protective membranes covering the brain and spinal cord. The vast majority meningiomas are benign, but they can still cause significant health issues depending on their size and location. Symptoms can include headaches, changes in vision, seizures, hearing loss or neurological deficits to name a few. Treatment options for meningiomas are generally surgical in nature although radiation may be utilized.

The Connection Between Depo-Provera and Meningiomas

The British Medical Journal recently published a French study of more than 100,000 women which found an association between Depo-Provera (medroxyprogesterone acetate) and meningiomas requiring surgical intervention. In fact, the study found an increased risk of 5.55% with prolonged use of Depo-Provera for a year or longer. This increased risk is significant.

What Should Women Do?

For women who have used Depo-Provera for at least a year (4 injections) and have been diagnosed with a meningioma, Anapol Weiss attorneys stand ready to hold the pharmaceutical company responsible and advocate for your rights.

If you have used/are using Depo-Provera but are not currently experiencing any issues, it is important to be vigilant about monitoring your health and discuss any concerns with your health care providers.