ABC News has reported that Australian women who developed meningioma tumors after Depo-Provera are considering filing a class action against Pfizer.
Excerpts:
Chanel Stuart-Clarke was just 31 when doctors discovered by accident she had a 15mm brain tumour. The 33-year-old is one of many women globally questioning whether their use of a popular contraceptive called Depo-Provera contributed to the development of their brain tumour.
In March, the British Medical Journal (BMJ) published a major study which found women who used Depo-Provera for more than a year had a five-to-six-fold increase of developing a meningioma compared to women who didn't use it.
Ms. Stuart-Clarke took the contraceptive for more than a decade to help stop heavy periods.
"No-one ever said you could potentially get a brain tumour," she said.
The BMJ research was a large study that looked at more than 108,000 women in France over a decade — including 18,000 who developed brain meningiomas — and compared a range of contraceptives. Study author epidemiologist Dr Noemie Roland said given its use was relatively low in France it was likely their results under-represented the real risk.
In response to the study's findings, patients are preparing lawsuits in the United States and Canada. In Australia, law firm Shine have announced they are recruiting participants for a possible class action.
Globally it's estimated 74 million women use Depo-Provera.
"Our results are not isolated internationally. They have been confirmed by results from Indonesian studies and recently by a large-scale study from the USA," Dr Roland said.
"We are very worried about this issue in the world. We fear of a significant prevalence of meningioma, where women are highly exposed to Depo-Provera," she said.
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In the United States, Anapol Weiss has filed a petition before the United States Judicial Panel on Multidistrict Litigation (JPML) seeking to consolidate all federal lawsuits involving Depo-Provera (Depot Medroxyprogesterone Acetate), a contraceptive injection linked to the development of cerebral meningiomas. The motion was filed on December 10, 2024.
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